Antibacterial Activities of Nepetalactones Against Public Health-Related Pathogens

The antimicrobial activities of ( Z,E)- and E,Z)-nepetalactones, 2 major compositional compounds from the essential oil catnip Nepeta cataria), were first discovered fly larval development media studies with over 98% inhibition bacterial growth. Further investigation demonstrated growth various species public health significance. Catnip showed antibacterial activity against 5 Gram-positive 9 Gram-negative bacteria. varied among original plant its as a blended mixture or an individual compound. Growth was observed Neisseria species, particularly strong sicca (with MICs ranging 0.5 to mg/mL) that provided comparable increased levels control produced by antibiotics (Ceftiofur Cephalothin). plant-based agents prevent delay emergence resistance in bacteria is discussed.